Ueber Inula graveolens1)

Hippokrates Ueber die Krankheiten III

irrelevant. Chemistry and the relations between science, technology, and industry are well surveyed by Crosland and Cardwell respectively. Forbes's essay on mathematical cosmography is not a comprehensive account but the story (albeit interesting) of a few German cartographers. Compared with other recent collections of essays in the history of science, this volume parades no party line: witness...

Ueber Das Verschwinden Der Θ-functionen

Two New Flavones from Inula grantioides

Inula grantioides (Boiss.) syn. /. cutchica Clarke is found in South West Pakistan, Karachi (Sindh), Kutch, Indus delta and Baluchistan. The plant is recommended for the treatment of asthma. This plant has not been subjected to chemical investiga­ tion so far. In the present paper we wish to report the isolation of two new flavones, grantionin 1 and grantioidinin 2 along with pluchidione 3, a k...

Antitumour activities of sesquiterpene lactones from Inula helenium and Inula japonica.

Eight sesquiterpene lactones were isolated from the roots of Inula helenium and flowers of I. japonica. Among them, isoalantolactone (3) and santamarine (6) exhibited significant growth inhibitory activities against gynecologic cancer cell lines, while others weakly inhibited the growth of the cell lines (IC50 < or = 100 microM). In addition, 3 significantly inhibited the tumour growth of S180 ...

Sesquiterpene lactones from Inula montana L.

Aerial parts of Inula montana were investigated for its sesquiterpenoid composition. Five sesquiterpene lactones, isoinuviscolide, gaillardin, 1beta-hydroxy-3beta-acetoxy-eudesm-4(15), 11(13)-dien-12-8beta-olide, pulchellin-C and pulchellin-E were identified for the first time in this plant. One of them, 1beta-hydroxy-3beta-acetoxy-eudesm-4(15),11(13)-dien-1 2-8beta-olide, is a novel natural pr...